Artemisinin

Name  Artemisinin
CAS#  63968-64-9
MF  C15H22o5
MW  282.33
Purity  99%HPLC
Package  25kg/drum
Storage  In sealed, cool and dry condition
Category  Ingredient
Inquiry

Description

Artemisinin (/ˌɑːtɪˈmsɪnɪn/) and its semisynthetic derivatives are a group of drugs used against malaria due to Plasmodium falciparum. It was discovered in 1972 by Tu Youyou, who was co-recipient of the 2015 Nobel Prize in Medicine for her discovery. Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P. falciparum malaria. Artemisinin is isolated from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine. A precursor compound can be produced using a genetically-engineered yeast, which is much more efficient than using the plant.

Chemically, artemisinin is a sesquiterpene lactone containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane ring is responsible for the drug’s mechanism of action. Few other natural compounds with such a peroxide bridge are known.

Artemisinin and its derivatives have been used for the treatment of malarial and parasitic worm (helminth) infections. They have the advantage over other drugs in having an ability to kill faster and kill all the life cycle stages of the parasites.

–Wikipedia