Product Name: Syn-AKE
CAS No.: 823202-99-9
INCI Name: Diaminobutyric acid benzylamide diacetate
MF: /
MW: 459.58
Appearance: White or almost white powder


Syn-Ake is a compound developed by Swiss pharmaceutical company Pentapharm that mimics a protein found in the venom of the Temple Viper. The protein, named Waglerin 1, is responsible for paralyzing the victim of the snake’s bite, as its venom is injected through its hollow fangs. According to Pentapharm, Syn-Ake works by preventing sodium ion uptake in muscles and keeping them relaxed to prevent the formation of deep expression lines. That is to say, it works in a way similar to Botox. In the 28-day trial of a Syn-Ake cream conducted on 45 volunteers by Pentapharm, 67% of the people claimed that wrinkle size was reduced by up to 52% after applying the cream twice daily.


The Syn-AKE peptide acts by reducing muscle cell contraction, smoothing mimic wrinkles in a short period, and is reversible. It is useful in anti-aging products and wrinkle treatment products, especially those targeting expression lines.

Recommended dosage: 1-4%