L-VCG

Product Name: L-VCG
CAS No.: 129499-78-1
INCI Name: Ascorbyl Glucoside
MF: C12H18O11
MW: 338.26
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Description

L-VCG is a well-known, safe and effective ascorbic acid derivative. It can release active Vitamin C in skin decomposed by glycosidase, which has powerful antioxidant properties and inhibits the synthesis of melanin. L-VCG also has very good anti-aging effect in skin. It is a popular skin lightening active ingredient worldwide.

Application:

It I recommended to use in skin whitening, anti-aging, anti-photoaging emulsion / essence, sun care and after sun products.

Recommended dosage > 2%.

Safety & Regulation

Clinical tests show that L-VCG has no hazard and side effects to human health or environment.

Efficacy

Skin lightening

Method:

  1. B16 melanoma cells were cultured until confluent (48hr). Theophy line (0.5m) was added to the culture during the last 24hr of culture;
  2. The cells were treated with L-VCG (2 mM) for 1-2 days;
  3. The cells were lysed with TCA and intracellular melanin content was measured.

L-VCG

Increase collagen synthesis, anti-wrinkle

Method:

  1. Human skin fibroblasts were incubated in the absence or presence of each collagen stimulator (0.25 mM) for 1-8 days.
  2. The relative rate of collagen synthesis to total protein synthesis was determined on 1st, 3rd, 5th and 8th

L-VCG-2

Remove free radicals. Help to repair sun damaged skin

Method:

  1. Creams containing 2% L-VCG or placebo were applied a two places on the inside of the right arm of 15 healthy adults.
  2. The creams were applied three times a day for 6 consecutive days.
  3. During this treatment, the arms were irradiated with UVA and UVB once per day for a total of 3 days.

L-VCG-3

Physical Properties

Assay: ≥98.0% HPLC Appearance: White or slight yellowish crystalline powder
Appearance of solution: 2% solution is clear Color of 5% solution: not more than 0.010 at 400nm
Specific Optical Rotation: 186.0-188.0o Melting range:158-163oC
Residue on Ignition: ≤0.2% Loss on Drying: ≤1.0%
Arsenic (As2O3): ≤1ppm Heavy Metals: ≤10ppm
Free ascorbic acid: ≤0.1% Free Glucose: ≤0.1%