Bioyouth™-NANA N-Acetylneuraminic Acid is an amino sugar naturally existing in the human body. It is found in large quantities in human breast milk and tissues. It is an essential component of mucoprotein, glycoprotein and glycolipid. It is mainly distributed on cell membrane glycoproteins and plays an important physiological role. It plays a role in skin protection, anti-wrinkle, antioxidant, moisturizing and so on. Based on the fermentation technology platform, Bloomage Biotech obtained Escherichia coli from soil by using high-throughput screening technology to produce Bioyouth™-NANA through fermentation process, which was filed by the National Medical Products Administration in August 2022. The filing number of the new cosmetic raw material is 20220026. It can be widely used in products such as lotion, cream, essence, facial mask, facial cleanser, toothpaste, mouthwash and shampoo.