Product Name  Genistein
Synonyms  4,5,7-trihydroxy-isoflavon
CAS  446-72-0
MF  C15H10O5
MW  270.24


Genistein is an isoflavone that is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated in 1899 from the dyer’s broom, Genista tinctoria; hence, the chemical name. The compound structure was established in 1926, when it was found to be identical with that of prunetol. It was chemically synthesized in 1928.


Genistein is 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4′. It is a phytoestrogenic isoflavone with antioxidant properties. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an EC [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a phytoestrogen and a plant metabolite. It is a conjugate acid of a genistein.