Product Name: AA2G / L-VCG
CAS No.: 129499-78-1
INCI Name: Ascorbyl Glucoside
MF: C12H18O11
MW: 338.26


AA2G / L-VCG (Ascorbyl Glucoside) is a well-known, safe and effective ascorbic acid derivative. It can release active Vitamin C in skin decomposed by glycosidase, which has powerful antioxidant properties and inhibits the synthesis of melanin. L-VCG also has very good anti-aging effect in skin. It is a popular skin lightening active ingredient worldwide.

It is recommended to use in skin whitening, anti-aging, anti-photoaging emulsion / essence, sun care and after sun products.

Recommended dosage: 2%.

Safety & Regulation:

Clinical tests show that L-VCG has no hazard and side effects to human health or environment.


Skin lightening


  1. B16 melanoma cells were cultured until confluent (48hr). Theophy line (0.5m) was added to the culture during the last 24hr of culture;
  2. The cells were treated with L-VCG (2 mM) for 1-2 days;
  3. The cells were lysed with TCA and intracellular melanin content was measured.


Increase collagen synthesis, anti-wrinkle


  1. Human skin fibroblasts were incubated in the absence or presence of each collagen stimulator (0.25 mM) for 1-8 days.
  2. The relative rate of collagen synthesis to total protein synthesis was determined on 1st, 3rd, 5th and 8th


Remove free radicals; Help to repair sun damaged skin


  1. Creams containing 2% L-VCG or placebo were applied a two places on the inside of the right arm of 15 healthy adults.
  2. The creams were applied three times a day for 6 consecutive days.
  3. During this treatment, the arms were irradiated with UVA and UVB once per day for a total of 3 days.


Physical Properties

Assay: ≥98.0% HPLC Appearance: White or slight yellowish crystalline powder
Appearance of solution: 2% solution is clear Color of 5% solution: not more than 0.010 at 400nm
Specific Optical Rotation: 186.0-188.0o Melting range:158-163oC
Residue on Ignition: ≤0.2% Loss on Drying: ≤1.0%
Arsenic (As2O3): ≤1ppm Heavy Metals: ≤10ppm
Free ascorbic acid: ≤0.1% Free Glucose: ≤0.1%